Biotech

Charles Baum manages Terremoto as chief executive officer

.Charles Baum, M.D., Ph.D., that managed Mirati Therapeutics' $ 5.8 billion purchase to Bristol Myers Squibb in 2013, is actually taking the command of younger biotech Terremoto Biosciences.Baum's "significant experience in drug development, and proven performance history in advancing high-impact medicines, are going to contribute," outbound chief executive officer Peter Thompson, M.D., said in a July 25 release. Thompson is going to maintain his seat as board chairperson..Baum, a qualified physician-scientist, was the creator, president and chief executive officer of oncology-focused Mirati. Prior to that, he assisted create cancer cells medications at Pfizer and also Schering-Plough..

Charles Baum, M.D., Ph.D.(( Mirati)).Now, Baum is going to act as CEO at Terremoto, a business building little molecules to target disease-causing healthy proteins-- like those located in cancerous tumor tissues-- utilizing covalent bonds. Existing treatments that use covalent bonds predominantly target the amino acid cysteine. Having said that, of the 20 amino acids that make up proteins, cysteine is actually the least typical. Terremoto is actually instead targeting one of the essential amino acids, amino acid lysine, which is actually discovered in mostly all proteins.By targeting amino acid lysine and also various other amino acids, Terremoto plans to address earlier undruggable ailments and make first-in-class medicines..The biotech, based in South San Francisco, brought up $75 million in collection A funding in 2022. A little bit of much more than a year later, the biotech greater than increased that variety in a $175 million set B.

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